Examples of Innovation in Medicine

The Moderna COVID-19 Vaccine (2024-2025 Formula) is an mRNA vaccine authorized for use in the United States for individuals aged 6 months to 11 years to prevent COVID-19. This vaccine is part of an ongoing effort to protect against emerging variants of the virus, with updated formulations designed to enhance efficacy. It consists of two doses administered intramuscularly, spaced one month apart, and is recommended even for those who have previously contracted COVID-19. Availability includes appointments at various healthcare locations, ensuring accessibility for families seeking to immunize their children.

EDIT-101 is an experimental gene editing therapy developed by Editas Medicine aimed at treating Leber congenital amaurosis 10 (LCA10), a genetic condition leading to vision loss. Utilizing CRISPR/Cas9 technology, EDIT-101 targets and deletes the IVS26 mutation in the CEP290 gene, which is responsible for the disorder. The treatment is administered through a subretinal injection, allowing for direct delivery to the affected retinal cells. Current clinical trials, such as the BRILLIANCE trial, are assessing its safety and efficacy in restoring vision for patients with LCA10.

Amwell is a telehealth platform that allows users to access medical care through online consultations with board-certified doctors and therapists, available 24/7 via phone, tablet, or computer. Patients can receive medical diagnoses, treatment, and prescriptions, which can be sent directly to their local pharmacy. The platform connects patients with providers, aiming to enhance access to affordable healthcare while offering the convenience of virtual visits from home or on-the-go. Amwell collaborates with hospitals and health systems to ensure high-quality care and improve the overall healthcare experience.

The Fitbit Charge 5 is a health and fitness tracker designed to monitor various aspects of physical well-being. It features built-in GPS, 24/7 heart rate monitoring, stress management tools, and sleep tracking capabilities. With a battery life of up to 7 days, it allows users to track their fitness routines and stress levels continuously. The device is equipped with advanced sensors that provide insights into how the body responds to stress, helping users to prioritize their health. Its thinner, rounded design makes it comfortable for daily wear, catering to fitness enthusiasts looking to enhance their overall wellness.

Aidoc offers a clinical AI platform known as aiOS™, designed to enhance medical imaging analysis by automatically detecting acute anomalies in scans. This software assists radiologists in accurately triaging patients and improving operational efficiency within healthcare systems. Utilizing Amazon Elastic Compute Cloud for training machine learning models, Aidoc's technology enables the identification of both expected and unexpected findings, thereby prioritizing urgent cases and ensuring that critical conditions are addressed promptly. The platform is recognized for its ability to integrate seamlessly into existing workflows, facilitating better patient outcomes and streamlining radiology processes.

Allevi offers a range of 3D bioprinters, including the Allevi 2 and Allevi 3 models, designed for bioprinting applications in tissue engineering, pharmaceuticals, and organ-on-a-chip research. These bioprinters utilize various printing techniques, such as extrusion and liquid deposition, to create complex geometries using living cells. Allevi also provides a selection of bioinks and related materials available for purchase through their online shop, facilitating the needs of researchers and laboratories in the bioprinting field. The Allevi online interface simplifies the bioprinting process, allowing users to easily connect their devices and manage their projects.